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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd427501b1849be40b05551a4760ce0df0a01822271ca98d21926172267417e02' 
  AND token = 'TJCkm21WAZV757Wlq2RVISgAoa5lDrNq1pI+dlHsyRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}