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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2287f2413266ccc37698e59f34d1ee7e844b0bbe1329ef7cf69f4d711a3dba5c' 
  AND token = '5Y4GcDxQthF5mec24wlykFA4drnMTjbQTkslv14KU5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}