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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8ace346264b37cb58c48100801cfc6d9701d0ce16fc54262871a2cc36b2e3a' 
  AND token = 'VLat8Zm1d1LB25VPzFVupUnmTMP8cs6V3wLc3RmlfRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}