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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d5ed2039a95594edd14f2496a3a8f4b786d9b3c9c6b9b54c76830eabc6c780' 
  AND token = 'jTJgMymT2a1R5j7RNoVdF9Vy/HtlrYYGwQUPIw13Ci0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}