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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e2963dc2ea40f00588d40a70a73eb93732e9aa25699ecdcfb0995c79175c0b' 
  AND token = '2qcF2jInmaB/nmh2qKHcnTHnPvQlZ/vK62jQOHg6IsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}