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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47578123402fa07d48cd93dbc00e0aedaf8e5dc2e01c9304f7f9d1e7b5f97921' 
  AND token = 'BFO23SUoujbG4i4r4fSsvydjue+b8kVVclOTuOfLyv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}