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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61bbe246297661b2cda0ae392de037ce43e3442238871a5d95e0060a4e6d10a' 
  AND token = '1yei+l05A1rgbGsFKnHsE3JgUS7eIsBUKBWTRV4D5mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}