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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bb7b5386b0a05e064e146acbdf5491ffa0f25ef2ac2809ac337b76d80aa1cb2' 
  AND token = 'QrqD6/XRNieSZ+5iEJA7F97iRnaOREQB4PykR3vjwXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}