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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5e4ff320c4f92e0fdbb998d6a58fbab46bdd7555149f0eaa25ae55db818edb' 
  AND token = 'YEPJumRCmwfQzocR0tCTT4t17TLvl7gMBv0jH+uV74k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}