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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e16229bc6878df4a1ea2f52669a178f7381a4d9ef93814c4afecace7708f021' 
  AND token = 'S5wD2nQKCSlRQEmtACE941nHmNzvpHbdfJPaQZYHqF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}