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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aba86ab072b6231cf34a480e8621789908187e3bd87c0158fab73c8c894a786c' 
  AND token = 'HVO7aG7Zo6A8GFr1Qw05OpsR8iTlOcQycYbtKBXQRL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}