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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4d7ed69eaa805bbd6783d8bb5eadc31ebe3b27da72e0441f6270012bc3a36b' 
  AND token = 'FMgWG2HK39VZuPalpCA96GUELlFJYBloNSkw3HirLEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}