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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae59cb6b52274f1dce8ad6b31a1b6b81ee3440b0e5b001dc2e04a5b95924230' 
  AND token = 'vI5rvDOk9jzCOlMTg/SMqaSb5yA6Z6atkgwE9Cj8d9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}