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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84d479898f4898fff97183f15f1725990c4402ebff2d9c5525ce8738f6d57227' 
  AND token = 'HrmYP8nqjqK0dAZkjN1PEmJDZWUYDMTctiRC9bwaEFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}