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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4b8c569cc5fcff26bc369c0952ef12d6eb483aaa1604493422affcd31307e67' 
  AND token = 'zmTOPVMG+riZUNfIy34AQOQvSQYM5b3Ys+p87QLkvzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}