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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dfc058126a35c73fe7d7547e06eac7226127558bfbf523b648a37cef10c1e0b' 
  AND token = 'N1qIG/jCE2niyIAUkqkJcU7NqthZX3MN7DIA4mAmKLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}