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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14263d5cd0fecebda46781c3afeb8ee159683b8d3be42c284c0f94b69b64b5d3' 
  AND token = 'csAe6OJgdQox9RX5XPjrmT93UCAlxyoB4GNF0SGxRfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}