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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b015ec10fd6800eeba5e5bac5766a1aec1ea5c6e2a67291923503e379edfb8f' 
  AND token = 'M5duG8zEx+wzY9Ox5901daQqFGoVmT2aM+aQx8Oi/Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}