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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c686d8ca8e1b14327f997f630d9c80d11b341d97866898a85d4fed7b2dbb27' 
  AND token = 'ONJwgmBm3LidsN2jj4cH6OIqRWIdZRWnK5oT7/8iggU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}