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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e5e9fdda3532454e144d69c63501927d0e21894791122d158ff0eb25a940c9' 
  AND token = 'jNO/Le/MfAIKS1x21JmxMuZQFlHOYIUc8mQd8Jt31fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}