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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e5c0123f058414857e0db7bf5c9697e77ef8d5fd3239ce1b63a6d139a12706e' 
  AND token = 'uxD7Nd1QAxBiPZ7rSXCBqvBACekaI/B/KPI7zk3LzKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}