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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c949e851c7e119a076292363a728e5f0504224708256c26e74014b7572521e1f' 
  AND token = 'XfuFuWAd18AWcDuW098XbyzZWxkSTEAsjgIPj1X28n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}