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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d1dc3f8bdce1646d6ce7a9caf80456600a7abc210e72578cadbba0ed770921f' 
  AND token = 'MQpmhFRiedGA1MLtTKlBCV4d7FwO4loZj0lTKTQ8Iq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}