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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1931aaa1db116b49f08c4beb048d4be566075bce37e4a42aff910112d2be90a' 
  AND token = 'DezK1lUEQUdburoMeiYzmNfQSdk49xEG5sP215SgQpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}