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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c0a743580fc0041e2229a9ddd6ccfc7b24ce8e22e69adc280858b82c7b6046b' 
  AND token = 'Uk1t0DCawDvlJ/X6H5nS53JiOoESZpFD2pazpsZcNkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}