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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6ceff0907323699a8dad4919af39ceb767a4dc7678c9f6d1828498f69c209a' 
  AND token = 'xHaB52U/kfiC0ceP8u9fvWaMVYVOxe5OuP0q531amek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}