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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f60d9d070c938fdf7a0b6e82c8c880042252fa762163abd07b9b029734cec83' 
  AND token = 'U+CU7TDRrpXEAsS7W2i/23jYxHl1TTkAF2f/BQUPtV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}