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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80354e485a2d15af61360aea75453458a30b3a6d22d6f29ccda9a3355ff0d414' 
  AND token = 'KhDAvt+OEk0pAU4VUFXl9yIUz75v0S7pWfKVw9EJMk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}