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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d297538ed4bffb3e53b041223ef7d4e559216453d4a31d8826a3b9f939feeaa' 
  AND token = 'nAj9OKNJ5dALJoh02buFK9o2S8HcOMQYqtmHUzU64CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}