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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c43ce9e469ab83b91d6a70b2a1eb63b361b062d3cece00666c8aa2ce5426fd6' 
  AND token = 'PDv6ZS50UeXVhE8zLszMWDe3IytipWZ0SQ3tgt6j1XE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}