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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6e661d19c011892058d78dffa5b53c0b12eeae102c724ed1d46bb35d26b260f' 
  AND token = 'CINz4ER8kzpXgsBZR4yEbCYX5ydLztgN0hhFl/OL9GA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}