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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145eabd22e1e7c361a5dc87ae70622608ee6dc2f8a387d6ad577df754a261ea6' 
  AND token = '9TTk1JA/h/wzAzXPESKN0NjWLfP3AWmKRhx3i5sOm7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}