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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13dc00163ce3e8fc1546764e605c26e2e4af1c122c9f9a313725a2f1ac709f71' 
  AND token = 'S0q4tuNhsAbJLCG3mDA/dVEy1/eq/HmdFG6N3T3XTaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}