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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd12901f1f5fcd4d45ff185268a30a39c341813353996007146d041ccf8d87f3c' 
  AND token = 'avXZ0uVe14yPhoBbVyyJRRCDy3oZmtVuopPxKz5Ahjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}