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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7921cdcdb29c1ce4ad21297dc5782a2dfdeb08fb7a9cb721ff041e24de0c3982' 
  AND token = 'yVoYsWudUNn/kycXQRUG5IlHfpdEsP2f2Bvw1rWrXys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}