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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46aae2d49f2d7c152bcd755a1c32c2825433dd65953b298d7bd387e6ee4f1a18' 
  AND token = 'jvR85JWCGh2sqBvecNDdhoUJs2tJs9nqLRGvRwLnK9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}