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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9c09c350ddcdba06eb96e90c89ee083612bb9515b2b3cd12a957d805e92a24e' 
  AND token = 'OS2xEhKelkc+TgbpCfE1oSdgV8TV/uYTMYz7c/h6tgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}