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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d8c80779f8d77b9cb1e7886c9e782db456f01a4afe1dfe8e4af874febe1666' 
  AND token = '1k+pJTSV1EG8MlA/T7KJ+1N4ZAo9ibyZZco/1wRFk5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}