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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2124cf1f2cafc84c7b762ba076a8a664adf1504b7722aa8c473b52fe5495f7e0' 
  AND token = 'vZDYrv7Bn4dDfYoFWf7L+bLc/1Af+4HnUGXADQyUqgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}