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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a166a8c262aa3648fb621830c1db29e93ef9d94d3b841d7dd1569c8b86fcc546' 
  AND token = 'NWws+P7eQPtyRqSRub1XKYofuhWUmWbHYuOU2H+Uz4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}