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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1bc4352771614c8c3229d49dcda1f234b51ec048cfe6631f09a136e4e993c4' 
  AND token = '4vkE4KvNOViOMXe1mS8vS0N2kiOSoTVKgCjGZNE0tI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}