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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344f5ffc10def60c2a56cd66b3c33f486e607789634d1e78d3a5fd7562e7ead6' 
  AND token = 'y05Ya4u547FMVtyeLcFGCc4hMkpkN1EaCJ6Qx/JzQ8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}