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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4d3e9accad2197406592b74237924d8d3307d2003d5d7129388bcbf19236f67' 
  AND token = 'VX1Ajij/7+a7zApNXgKLAetM1VMWy9R+Lg7tfsOZ3eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}