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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a2b2eddcd94eb7d80eb0b476d9bded5bdde6b41d1bde31f0654e7046fcdfe3' 
  AND token = 'tko2Chi6v4v3E7c1gZF4Thdgbza8OROpVdczA6IlG5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}