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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a291701d1d36d6ea24b690e80fd464121fe638ef3cdcbce2ce35a6535730fe87' 
  AND token = '4OTACB9HrN2Omh1weDPkkSAoW+fyEMZvrtcsjwZC5p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}