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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53635fe5129fd5d5461d7d4fc4b86ef4b436949ad36bc0fee769b158895b8d47' 
  AND token = 'l9xktIs8yCALHfdQkFkMuLfYi4TjpNjBsjzF+CUw+9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}