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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e10f1fc8a784a6bc6f70e459a03ef00a5bc77f43de6f1754bd9ad278f417376' 
  AND token = 'aevQeXmZFP5kHMSL6Tgmb3lLo0dIGz8R6nC77JhBpQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}