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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fdcf9353f52052394a90e8f67069906a60493e2a05e1ba1dbc413cd45a64cbb' 
  AND token = 'xzPnoiRwtnrj/Ch6Jc+PbAckEOOzXVoTS1s5CuONUY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}