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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd86f8ba3debf4b4461e5a2f53748e52eb05a3ed4507782dfc65e3356d17b41bd' 
  AND token = 'rogIwt3hHPIx6D3208wClTMZMcTP+tR2ZLZ4hs/2V1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}