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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd541db6ae6c16316b8bac859e75d36bb01e80b653b5e32922fd0908d2d34ff1' 
  AND token = 'RQFoek50SX2QuPWD8On5/E5tFSGcAH3ShY6SNzlVJAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}